Some people think that “everything is going well” after the vaccine is immunized, and basically does not do antibody testing, and do not evaluate whether the chicken antibodies can effectively resist the virus attack. After the antibody is tested, only the average is looked at, and the antibody uniformity is ignored. In fact, the disease in the flock is precisely caused by the uneven antibody. Chickens with low disease resistance are prone to infection and disease. After some chickens become ill, the disease gradually spreads and eventually leads to the disease in the whole flock.
Too much care about the price of vaccines, only to control the cost of immunization. Must choose effective products, combined with antibody testing, scientific immunization is the way to control costs, products that can solve problems are the cheapest products, and solutions that can solve problems are the lowest cost methods.
Vaccines with different strains are used for the first, second and re-immunization. It is always believed that the protection rate of using a few more strains will be better. In fact, on the contrary, the antibody needs to be repeatedly immunized to increase significantly. For example, our children are vaccinated with hepatitis B vaccine as soon as they are born, and then repeated immunizations with the same vaccine one month and six months later can produce effective antibodies.
Most people think that high-temperature viral diseases will no longer occur, so many people relax their vaccination in summer. Through a large amount of laboratory data analysis, it is found that viral diseases are still prevalent in summer, but they are lighter than winter and spring. If supplementation is not paid attention to in summer, the antibody level of the chickens is low, and the heat stress is strengthened. The chickens have insufficient feed intake for a long time and lack of nutrition. After autumn, the temperature difference between day and night will increase, and viral diseases will be prevalent. The cause of the high incidence of diseases in autumn and winter, so the immunity in summer cannot be relaxed.
Immunization program settings are unreasonable.
- The freeze-dried vaccine mainly produces local mucosal antibodies after immunization. Respiratory virus (Newcastle disease, spreading, etc.) vaccines contact the upper respiratory tract mucosa, stimulate the respiratory mucosa to produce cellular immunity and generate local mucosal antibodies, which can prevent this type of virus infection. Therefore, the lyophilized vaccine has the best immunity effect by spraying, followed by eye spot immunity, and drinking water immunity is the worst.
- Oil vaccines are injected slowly, and antigens are released slowly, mainly producing humoral antibodies, which are the antibodies we often detect. They are the main force against disease and infection. Taking into account the stress response and vaccine absorption problems caused by oil vaccine injections, oil vaccines have the best immunity The method is subcutaneous injection in the neck. The stress response is small and the absorption is fast. The chest muscle injection has a large stress response and is not easy to absorb. The leg muscle injection has the worst effect and the most stress response, which is not conducive to the health of the chickens. In addition, the oil vaccine should be pre-warmed with warm water before injection to increase the vaccine temperature to 35-38°C.
In summary, freeze-dried vaccines and oil vaccines play different roles and require joint immunization.
It is believed that antibodies will be produced after the vaccine is immunized. In fact, they are not. Take Newcastle disease as an example. About 4 (the critical value of onset). At this time, immunization is the best time. After that, the antibody slowly rises, but the increase is not large, generally 5-6, and lasts to about 45 days of age. Therefore, chickens aged 35 to 45 days need to be carefully taken care of, otherwise they will There is a problem. At this time, once the onset is a typical case, the antibody will only rise sharply after 45 days of age. This is the law of antibody production.
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